Mnemonic theories of hippocampal function.
نویسندگان
چکیده
Although mnemonic interpretations of hippocampal function in people have been readily accepted for many years, similar interpretations of hippocampal function in animals have received a number of challenges. This article reviews two of these challenges, shows how they were resolved in favor of some kind of mnemonic interpretation, and then suggests ways in which these types of interpretations must change in order to encompass new data.
منابع مشابه
Decoding signal processing in thalamo-hippocampal circuitry: implications for theories of memory and spatial processing.
A major tool in understanding how information is processed in the brain is the analysis of neuronal output at each hierarchical level through which neurophysiological signals are propagated. Since the experimental brain operation performed on Henry Gustav Molaison (known as patient H.M.) in 1953, the hippocampal formation has gained special attention, resulting in a very large number of studies...
متن کاملHippocampus and contextual fear conditioning: recent controversies and advances.
Dorsal hippocampal (DH) lesions produce a severe deficit in recently, but not remotely, acquired contextual fear without impairing memory of discrete training stimuli, i.e., DH lesions produce an anterograde and time-limited retrograde amnesia specific to contextual memory. These data are consistent with the standard model which posits temporary involvement of the hippocampus in recent memory m...
متن کاملIt's In My Eyes, but It Doesn't Look that Way to Me
In this issue of Neuron, Hannula and Ranganath provide striking evidence that hippocampal activity predicts eye movements that reveal memory for the past even when participants' overt memory decisions are in error. Their findings bear on an ongoing debate about the relationship between mnemonic awareness and hippocampal function.
متن کاملTHEORETICAL REVIEW Mechanisms for Widespread Hippocampal Involvement in Cognition
The quintessential memory system in the human brain—the hippocampus and surrounding medial temporal lobe—is often treated as a module for the formation of conscious, or declarative, memories. However, growing evidence suggests that the hippocampus plays a broader role in memory and cognition and that theories organizing memory into strictly dedicated systems may need to be updated. We first con...
متن کاملAcetylcholine release in the hippocampus: effects of cholinergic and GABAergic compounds in the medial septal area.
The medial septal area (MSA) contains cholinergic and GABAergic neurons that send projections to the hippocampus. These neurons have both cholinergic and GABAergic receptors. This study was designed to determine the effects of intraseptal infusions of cholinergic and GABAergic drugs, which alter mnemonic processes, on hippocampal acetylcholine (ACh) release. Hippocampal ACh release was assessed...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Behavioral neuroscience
دوره 100 6 شماره
صفحات -
تاریخ انتشار 1986